Neuronal expression of Mgat1 rescues the shortened life span of Drosophila Mgat11 null mutants and increases life span

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Asparagus racemosus extract increases the life span in Drosophila melanogaster

Article history: Received on: 31/07/2015 Revised on: 11/08/2015 Accepted on: 20/08/2015 Available online: 24/08/2015 Free radicals and oxidative stress are recognized as important factors in the biology of aging as well as in many age-related diseases. Dietary antioxidant plays a potential role in the reduction of age-related diseases. Many medicinal plants are rich source of antioxidants and p...

متن کامل

“the effect of risk aversion on the demand for life insurance: the case of iranian life insurance market”

abstract: about 60% of total premium of insurance industry is pertained?to life policies in the world; while the life insurance total premium in iran is less than 6% of total premium in insurance industry in 2008 (sigma, no 3/2009). among the reasons that discourage the life insurance industry is the problem of adverse selection. adverse selection theory describes a situation where the inf...

15 صفحه اول

Neuronal Expression of p53 Dominant-Negative Proteins in Adult Drosophila melanogaster Extends Life Span

Hyperactivation of p53 leads to a reduction in tumor formation and an unexpected shortening of life span in two different model systems . The decreased life span occurs with signs of accelerated aging, such as osteoporosis, reduction in body weight, atrophy of organs, decreased stress resistance, and depletion of hematopoietic stem cells. These observations suggest a role for p53 in the determi...

متن کامل

β-N-Methylamino-L-alanine Induces Neurological Deficits and Shortened Life Span in Drosophila

The neurotoxic non-protein amino acid, β-N-methylamino-L-alanine (BMAA), was first associated with the high incidence of Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) in Guam. Recently, BMAA has been implicated as a fierce environmental factor that contributes to the etiology of Alzheimer's and Parkinson's diseases, in addition to ALS. However, the toxicity of BMAA in vi...

متن کامل

Life Span and Disability

Psychiatric functioning and disability have historically been considered separate from the broader disability field and have been measured differently than other medical conditions. This paper provides an overview of the current concepts and international advances in the classification of psychiatric disability and explores the controversies and goals within the proposed systems. It highlights ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2010

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.1004431107